Two Successful Drugs on Trial…
There are two important clinical trials now recruiting – one in Europe, one across the United States – testing the combination of Jakafi with an HDAC inhibitor, Panobinostat. On its own, this drug has recorded a Complete Response – reversal of fibrosis and restoration of hematopoietic function — in an MF patient. Expectations are high for its coupling with Jakafi. The story <<The Silent Gene>> is in the new MPNforum
There’s another clinical trial scheduled for late this summer of a completely different drug, PRM -151, that has been successful in reversing fibrosis. That story – along with Dr. Robyn Emmanuel’s update on patient interventions from the Fatigue Project — is also in the April 15 MPNforum, published tomorrow.
Enjoy…and if you happen to find any typos, we’re still pre-publication so please do let me know (zhenyasenyak@gmail.,com).