International MPN News, Science & Opinion

To finish the work

 

                                    

Without him.

 

The true leader of our MPN world has gone.

Camera shy, avoiding personal publicity, his relentless pursuit of a cure for MPNs is largely unrecognized.

And yet he has been the driving force behind virtually every therapeutic and scientific advance we’ve enjoyed for the past decade.

Before leaving, he opened new research lines that are only now being explored. And he left us the infrastructure that can take us all the way to a cure.

What remains is for us to roll up our sleeves and help finish the work he began. He has shown us how. (Story here).

 

 

 

Ellen’s back and she brought us a fresh update (December 26, 2017) of the List.

Now 273 Patient-recommended hematologists from 23 nations and 41 states.

You can find it here.

And best wishes from all of us at MPNforum for a Happy, peaceful and creative New Year.

 

 

 

 

 

 

We’re going to get a new MF/PV drug

Yes, it’s true!   Federatinib is back…and in the hands of its original creator. Forget the Sanofi nightmare. The FDA has lifted its clinical hold and Impact Biomedicines (Drs John Hood, Catriona Jamieson & Co.) is using Sanofi’s Phase III dataset and moving full speed to get this Jakafi competitor in our hands.  And a strange twist to the story. Independent panel determines there never was any reason to abort the trial. Sanofi closed up shop before taking a closer look.

Plus News from ASH…an overview of the MPN scene by the Dean of Hematologists… The latest MPN Hero… A Scottsdale type meeting in San Antonio … Exploring the way interferon really works…plus the new List of Hematologists…and more.  Enjoy

It’s all right herehttps://mpnforum.com/december-2017-the-ash-issue/

Happy Holidays from all of us at MPNforum

 

*This is an ADVANCE copy of the issue that will be published Thursday.  Please send any corrections, typos, comments to ourMPNforum@gmail.com. Thanks.

 

 

The Zhenya Senyak Comeback Road Show…

by Zhen

The Zhenya Senyak Comeback Road Show…

To celebrate my shaky return to an active life, I thought I’d share some thoughts on the dangers of second cancers for MPN patients….A graphic illustration of Kafka and Cachexia… My take on the needs and strengths of our MPN patient community in the US… and a quick news report on the surprising dangers associated with checkpoint inhibitor therapy.

“It ain’t easy… but it can be done. Maybe..”

Ciao bello..

Zhen

Here’s a chance to revisit this major MPN event. It’s…

The Cotter Field Report

…a closeup look at the people and events by MPN patient Mary Cotter.

This year’s CR&T started in tragedy and ended in hope. Along the way Mary covers the program and wonders what it is that makes these meeting so essential to our community.  It’s all

at:  https://mpnforum.com/crt-the-cotter-report/

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Last Call

LAST CALL…

For the Very Last Time – MPNforum goes to ASH. Join us

The American Society of Hematology year-end meeting is the MPN science and medicine main event .

In the past 20 years, every single major study, drug, and breakthrough was announced at ASH. Nobody covers ASH like MPNforum… interviews, analyses, reports, photographs. We broke the news on Imetelstat, CAL-R, CRISPR gene therapy, Momelotinib. Pacritinib and much more..

This year, following the stunning cure of a leukemia using gene therapy, we have more reason than ever to drill down into the lab results and reports of clinical trials. It will all be in the December issue of MPNforum…

Your Small Donation can

Sponsor that work…

Support the on-line availability of all back MPNforum backissues…

Help launch MPNforum’s new publication, MPN Science and Medicine.

This is our last call for 2017 Small Donation Sponsors.

Here’s how the Small Donation program works.

Click the Donate button and contribute any amount from $5 to $100nothing higher please. We return the difference and have to pay a fee. Donors will be listed as Sponsors in the last regular issue of MPNforum in December– unless you let us know you refer to be anonymous.

And thank you for your support!
The MPNforum/MPN Science & Medicine team OurMPNforum@gmail.com

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MPNforum, PO Box 17142, Asheville, NC 28816
Donations to MPNforum are not tax-deductible

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Stand with us.

MPNforum Magazine will suspend publication after our Winter issue. All articles, columns, features, lists and resources – more than 700 web pages —  will continue to be available on-line, at http://www.mpnforum.com.  In its place a new family member:  MPN Science & Medicine.  Here’s why:

 A tale of two cancers

From Zhenya: ” It took a second cancer to bring it home to me. MPN research and science is booming.  We are closing in on a cure!

The only therapies available for my recently diagnosed colorectal cancer are variations on the ancient cut, burn, chemo.  In the MPNs and related blood cancers, research and molecular biology have leaped ahead from early work in JAK inhibitors, to CRISPR boosted immunotherapy,– a cure for a leukemia–  PD 1 inhibition, stem cell research, checkpoint inhibitors, combination drugs,  anti-inflammatory studies and the unraveling of associated epigenetics.”

  – a change of focus

 The idea behind MPNforum’s new publication MPN Science & Medicine is to focus on the most significant research and testing affecting MPN therapy, That includes trolling the labs, universities, drug companies and evaluating clinical trials.

One Hillel of an choice

Staffing MPN Science & Medicine there’s a small volunteer MPNforum team that reliably covers news and loyal MPN researchers and medical specialists on our side.. We have the capabilities to research, analyze and report on science and medicine. That’s my personal mission. And to paraphrase the First century Rabbi Hillel, “If not me who? And if not with you, with whom?. nd if not now, when?”

We pay the bills

 To do this work, we pay the bills. The travel, internet, production, equipment, lights, etc. We are a fully independent all-volunteer group of patients and caregivers and accept no ads, no grants, no subscription fees.  Every operating dime comes from the MPN community.

MPNforum is free and independent because of our sponsors. Last year 137 men and women via small donations provided the financial support that kept the Forum freely available on the Internet for our worldwide community  —   12,000 readers per issue and well over 625,000 visitors to our pages.

 And you can join them  right now and become one of the Charming Gardeners supporting our international MPN community  It’s quick and easy

   Here’s how the Small Donation program works.

Click the Donate button and contribute any amount from $5 to $100nothing higher please. We return the difference and have to pay a fee. Donors will be listed as Sponsors in the last MPNforum – the December issue – unless you let us know you refer to be anonymous.

And thank you for your support!

    The MPNforum/MPN Science & Medicine  team
   OurMPNforum@gmail.com

MPNforum, PO Box 17142, Asheville, NC 28816
Donations to MPNforum are not tax-deductible

 

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